• View As List
• View As Table

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11330 Species: Mus musculus RGD Object: Gene Symbol: Sod2 Name: superoxide dismutase 2, mitochondrial

Acc ID: CHEBI:4784 Term: enalapril Definition: A dicarboxylic acid monoester that is ethyl 4-phenylbutanoate in which a hydrogen alpha to the carboxy group is substituted by the amino group of L-alanyl-L-proline (S-configuration). CasRN: 75847-73-3 Chemical ID: MESH:D004656

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases activity	ISO	RGD:3732	6480464	CTD	Enalapril results in decreased activity of SOD2 protein	PMID:18765277
multiple interactions	EXP		6480464	CTD	[paricalcitol co-treated with Enalapril] results in decreased expression of SOD2 protein	PMID:20720404
decreases expression	EXP		6480464	CTD	Enalapril results in decreased expression of SOD2 protein	PMID:20720404