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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2397
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cpt1b
Name: carnitine palmitoyltransferase 1B
Acc ID: CHEBI:47612
Term: bezafibrate
Definition: A monocarboxylic acid amide obtained by the formal condensation of the carboxy group of 4-chlorobenzoic acid with the amino group of 2-[4-(2-aminoethyl)phenoxy]-2-methylpropanoic acid. Benafibrate is used for the treatment of hyperlipidaemia.
Chemical ID: MESH:D001629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cpt1bincreases expressionEXP 6480464CTDBezafibrate results in increased expression of CPT1B mRNAPMID:11473052
Cpt1bincreases expressionISOCpt1b (Mus musculus)6480464CTDBezafibrate results in increased expression of CPT1B mRNAPMID:11056218 PMID:21324916
Cpt1bmultiple interactionsISOCpt1b (Mus musculus)6480464CTDPPARA protein affects the reaction [Bezafibrate results in increased expression of CPT1B mRNA]PMID:21324916
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