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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620816 Species: Rattus norvegicus RGD Object: Gene Symbol: Pdcd4 Name: programmed cell death 4

Acc ID: CHEBI:47381 Term: diclofenac Definition: A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position. CasRN: 15307-86-5 Chemical ID: MESH:D004008

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:732159	6480464	CTD	Diclofenac results in decreased expression of PDCD4 mRNA	PMID:21873647
increases expression	ISO	RGD:732159	6480464	CTD	Diclofenac results in increased expression of PDCD4 mRNA	PMID:21873647