GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccnd1 | decreases activity | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | alvocidib results in decreased activity of CCND1 protein | PMID:10441105 | Ccnd1 | decreases expression | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | alvocidib results in decreased expression of CCND1 protein | PMID:12517783 PMID:12589031 PMID:16905211 PMID:9802881 PMID:9829756 | Ccnd1 | decreases expression | ISO | Ccnd1 (Mus musculus) | 6480464 | CTD | alvocidib results in decreased expression of CCND1 protein | PMID:12734434 | Ccnd1 | multiple interactions | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in decreased expression of CCND1 protein | PMID:15634644 | |
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