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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734400 Species: Homo sapiens RGD Object: Gene Symbol: ATP5A1 Name: ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle

Acc ID: CHEBI:472805 Term: ouabain Definition: A multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+(/K)+)-ATPase (sodium pump). CasRN: 630-60-4 Chemical ID: MESH:D010042

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects expression	EXP		6480464	CTD	Ouabain affects the expression of ATP5A1 protein	PMID:17268060