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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621505
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk7
Name: mitogen-activated protein kinase 7
Acc ID: CHEBI:472805
Term: ouabain
Definition: A steroid hormone that is a multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+)/K(+)-ATPase (sodium pump). It has been isolated naturally from Strophanthus gratus.
Chemical ID: MESH:D010042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk7multiple interactionsISOMAPK7 (Homo sapiens)6480464CTDOuabain inhibits the reaction [palytoxin results in increased phosphorylation of and results in increased activity of MAPK7 protein]PMID:19716839
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