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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2645
Species: Rattus norvegicus
RGD Object: Gene
Symbol: G6pd
Name: glucose-6-phosphate dehydrogenase
Acc ID: CHEBI:47217
Term: arsane
Definition: An arsine that has formula 77.94542.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
G6pddecreases activityEXP 6480464CTDArsenic results in decreased activity of G6PD proteinPMID:21864513 PMID:22229868
G6pdmultiple interactionsEXP 6480464CTDsilybin inhibits the reaction [Arsenic results in decreased activity of G6PD protein]PMID:22229868
G6pdmultiple interactionsISOG6pdx (Mus musculus)6480464CTD[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of G6PD proteinPMID:32226249
G6pdmultiple interactionsISOG6PD (Homo sapiens)6480464CTD[sodium arsenate results in increased abundance of Arsenic] which results in increased expression of G6PD mRNAPMID:32525701
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