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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2200
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2l1
Name: Bcl2-like 1
Acc ID: CHEBI:47217
Term: arsane
Definition: An arsine that has formula 77.94542.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2l1increases expressionEXP 6480464CTDArsenic results in increased expression of BCL2L1 proteinPMID:11756236
Bcl2l1increases expressionISOBCL2L1 (Homo sapiens)6480464CTDArsenic results in increased expression of BCL2L1 mRNAPMID:19962721
Bcl2l1multiple interactionsISOBCL2L1 (Homo sapiens)6480464CTD[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of BCL2L1 protein; [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of BCL2L1 mRNA; [sodium arsenite results in increased abundance of Arsenic] promotes the reaction [ATF3 protein binds to BCL2L1 promoter]; [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of BCL2L1 mRNA; [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of BCL2L1 protein; ATF3 protein affects the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of BCL2L1 mRNA]; ATF3 protein affects the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of BCL2L1 protein]PMID:32525701 PMID:32802178 PMID:33921748
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