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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2141
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aqp1
Name: aquaporin 1
Acc ID: CHEBI:47217
Term: arsane
Definition: An arsine that has formula 77.94542.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aqp1decreases expressionISOAQP1 (Homo sapiens)6480464CTDArsenic results in decreased expression of AQP1 mRNAPMID:30746931
Aqp1increases methylationISOAQP1 (Homo sapiens)6480464CTDArsenic results in increased methylation of AQP1 genePMID:30746931
Aqp1multiple interactionsISOAqp1 (Mus musculus)6480464CTD[APOE protein affects the susceptibility to Arsenic] which affects the expression of AQP1 mRNAPMID:22719926
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