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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305332
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mdm2
Name: MDM2 proto-oncogene
Acc ID: CHEBI:47217
Term: arsane
Definition: An arsine that has formula 77.94542.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mdm2affects methylationISOMDM2 (Homo sapiens)6480464CTDArsenic affects the methylation of MDM2 genePMID:25304211
Mdm2affects response to substanceISOMDM2 (Homo sapiens)6480464CTDMDM2 SNP affects the susceptibility to ArsenicPMID:21982800
Mdm2increases expressionISOMDM2 (Homo sapiens)6480464CTDArsenic results in increased expression of MDM2 proteinPMID:35821281
Mdm2multiple interactionsISOMDM2 (Homo sapiens)6480464CTDUSP7 protein affects the reaction [Arsenic results in increased expression of MDM2 protein]PMID:35821281
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