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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:46742
Term: Nutlin-3
Definition: A Nutlin that has formula C30H30Cl2N4O4.
Chemical ID: MESH:C482205
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTDnutlin 3 results in decreased expression of BCL2; nutlin 3 results in decreased expression of BCL2 proteinPMID:20422343 PMID:35213076
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTDPVT1 protein inhibits the reaction [nutlin 3 results in decreased expression of BCL2 protein]PMID:35213076
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