GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305515
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rgs17
Name: regulator of G-protein signaling 17
Acc ID: CHEBI:4672
Term: docetaxel anhydrous
Definition: A tetracyclic diterpenoid that is paclitaxel with the N-benzyloxycarbonyl group replaced by N-tert-butoxycarbonyl, and the acetoxy group at position 10 replaced by a hydroxy group.
CasRN: 114977-28-5
Chemical ID: MESH:C067311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases response to substanceISORGD:13135876480464CTDRGS17 protein results in increased susceptibility to docetaxel

PMID:21044322
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