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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619991
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vegfa
Name: vascular endothelial growth factor A
Acc ID: CHEBI:46666
Term: crocidolite asbestos
Definition: null
Chemical ID: MESH:D017638
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfaincreases expressionISOVEGFA (Homo sapiens)6480464CTDAsbestos, Crocidolite results in increased expression of VEGFA mRNAPMID:25757056
Vegfaincreases expressionISOVegfa (Mus musculus)6480464CTDAsbestos, Crocidolite results in increased expression of VEGFA proteinPMID:29507420
Vegfaincreases secretionISOVEGFA (Homo sapiens)6480464CTDAsbestos, Crocidolite results in increased secretion of VEGFA proteinPMID:21762757
Vegfamultiple interactionsISOVEGFA (Homo sapiens)6480464CTDRTKI cpd inhibits the reaction [Asbestos, Crocidolite results in increased secretion of VEGFA protein]PMID:21762757
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