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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3733
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sod3
Name: superoxide dismutase 3
Acc ID: CHEBI:46661
Term: asbestos
Definition: Fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements.
Chemical ID: MESH:D001194
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod3affects response to substanceISOSod3 (Mus musculus)6480464CTDSOD3 gene polymorphism affects the susceptibility to Asbestos; SOD3 protein affects the susceptibility to AsbestosPMID:16458190 PMID:21362472
Sod3increases secretionISOSod3 (Mus musculus)6480464CTDAsbestos results in increased secretion of SOD3 proteinPMID:21362472
Sod3multiple interactionsISOSod3 (Mus musculus)6480464CTDSOD3 gene polymorphism promotes the reaction [Asbestos results in increased secretion of SOD3 protein]PMID:21362472
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