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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:46632
Term: clonidine (amino form)
Definition: A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Chemical ID: MESH:D003000
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3increases expressionEXP 6480464CTDClonidine results in increased expression of CASP3 mRNAPMID:15351510
Casp3increases activityISOCASP3 (Homo sapiens)6480464CTDClonidine results in increased activity of CASP3 proteinPMID:28115640
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