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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2686
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gh1
Name: growth hormone 1
Acc ID: CHEBI:46631
Term: clonidine
Definition: null
Chemical ID: MESH:D003000
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gh1increases secretionEXP 6480464CTDClonidine results in increased secretion of GH1 proteinPMID:15099682
Gh1multiple interactionsEXP 6480464CTDCocaine inhibits the reaction [Clonidine results in increased secretion of GH1 protein]PMID:15099682
Gh1increases expressionISOGH1 (Homo sapiens)6480464CTDClonidine results in increased expression of GH1; Clonidine results in increased expression of GH1 proteinPMID:2568210 PMID:3007707 PMID:6150000 PMID:707001
Gh1increases secretionISOGH1 (Homo sapiens)6480464CTDClonidine results in increased secretion of GH1 proteinPMID:17889730
Gh1multiple interactionsISOGH1 (Homo sapiens)6480464CTDL 657743 inhibits the reaction [Clonidine results in increased expression of GH1 protein]PMID:2568210
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