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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552629 Species: Mus musculus RGD Object: Gene Symbol: Nr1i3 Name: nuclear receptor subfamily 1, group I, member 3

Acc ID: CHEBI:4636 Term: diphenhydramine Definition: The benzhydryl ether of 2-(dimethylamino)ethanol. CasRN: 58-73-1 Chemical ID: MESH:D004155

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:1344163	6480464	CTD	[Diphenhydramine co-treated with PK 11195] binds to and results in increased activity of NR1I3 protein alternative form	PMID:20869355