Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620248
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb4
Name: ATP binding cassette subfamily B member 4
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb4increases expressionEXP 6480464CTDAcetaminophen results in increased expression of ABCB4 mRNAPMID:33387578
Abcb4decreases expressionISOAbcb4 (Mus musculus)6480464CTDAcetaminophen results in decreased expression of ABCB4 mRNAPMID:29246445
Abcb4decreases expressionISOABCB4 (Homo sapiens)6480464CTDAcetaminophen results in decreased expression of ABCB4 mRNAPMID:21420995 PMID:29067470
Abcb4multiple interactionsISOAbcb4 (Mus musculus)6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of ABCB4 mRNA; PANX1 gene mutant form inhibits the reaction [Acetaminophen results in decreased expression of ABCB4 mRNA]; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ABCB4 mRNA]PMID:17585979 PMID:29246445
Abcb4multiple interactionsISOABCB4 (Homo sapiens)6480464CTD[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in decreased expression of ABCB4 mRNAPMID:33819548
Go Back to source page   Continue to Ontology report