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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10698
Species: Mus musculus
RGD Object: Gene
Symbol: Gstm2
Name: glutathione S-transferase, mu 2
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gstm2affects expressionEXP 6480464CTDAcetaminophen affects the expression of GSTM2 mRNA; Acetaminophen affects the expression of GSTM5 mRNAPMID:17562736
Gstm2decreases expressionEXP 6480464CTDAcetaminophen results in decreased expression of GSTM2 mRNAPMID:16611625
Gstm2multiple interactionsEXP 6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of GSTM2 mRNA; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of GSTM2 mRNA]PMID:17585979
Gstm2decreases expressionISOGstm2 (Rattus norvegicus)6480464CTDAcetaminophen results in decreased expression of GSTM2 mRNAPMID:18346771 PMID:33387578
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