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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:46044
Term: 1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea
Definition: A 1,3-thiazole that has formula C12H12N4O4S.
Chemical ID: MESH:C479831
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTD[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in increased expression of BAX protein]PMID:20540935
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