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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735778
Species: Mus musculus
RGD Object: Gene
Symbol: Scn1a
Name: sodium channel, voltage-gated, type I, alpha
Acc ID: CHEBI:45980
Term: tacrine
Definition: A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
Chemical ID: MESH:D013619
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scn1aincreases expressionISOScn1a (Rattus norvegicus)6480464CTDTacrine results in increased expression of SCN1A mRNAPMID:12832660
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