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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2459 Species: Rattus norvegicus RGD Object: Gene Symbol: Cyp1a2 Name: cytochrome P450, family 1, subfamily a, polypeptide 2

Acc ID: CHEBI:45906 Term: suramin Definition: A naphthalenesulfonic acid that has formula C51H40N6O23S6. CasRN: 145-63-1 Chemical ID: MESH:D013498

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases activity	ISO	RGD:735711	6480464	CTD	Suramin results in decreased activity of CYP1A2 protein	PMID:11124226