GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | increases phosphorylation | EXP | | 6480464 | CTD | Paclitaxel results in increased phosphorylation of RELA protein | PMID:30414958 | Rela | multiple interactions | EXP | | 6480464 | CTD | 1-((3-benzyl-3-methyl-2,3-dihydro-1-benzofuran-6-yl)carbonyl)piperidine inhibits the reaction [Paclitaxel results in increased phosphorylation of RELA protein]; Paclitaxel promotes the reaction [RELA protein binds to IRF8 promoter] | PMID:30414958 | Rela | decreases expression | ISO | RELA (Homo sapiens) | 6480464 | CTD | Paclitaxel results in decreased expression of RELA protein | PMID:17701358 PMID:18098270 | Rela | increases phosphorylation | ISO | Rela (Mus musculus) | 6480464 | CTD | Paclitaxel results in increased phosphorylation of RELA protein | PMID:36898573 | Rela | multiple interactions | ISO | RELA (Homo sapiens) | 6480464 | CTD | [Gemcitabine co-treated with Doxorubicin co-treated with Paclitaxel] affects the localization of RELA protein; [Gemcitabine co-treated with Doxorubicin co-treated with Paclitaxel] results in increased expression of RELA protein; [Paclitaxel co-treated with F2 protein] affects the localization of RELA protein; [Paclitaxel co-treated with Metformin] results in decreased expression of RELA mRNA; [Paclitaxel co-treated with Tropisetron] results in decreased expression of RELA protein; [Tretinoin co-treated with Paclitaxel] results in decreased expression of RELA protein; caffeic acid phenethyl ester inhibits the reaction [Paclitaxel results in increased activity of RELA protein]; Curcumin inhibits the reaction [Paclitaxel results in increased activity of RELA protein]; Paclitaxel promotes the reaction [voacamine affects the localization of RELA protein] | PMID:15291876 PMID:16243823 PMID:17039268 PMID:17701358 PMID:18098270 PMID:19944065 PMID:29309887 PMID:34654991 PMID:34856211 | Rela | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | [Paclitaxel co-treated with Tropisetron] results in decreased expression of RELA protein; ITGAM protein affects the reaction [Paclitaxel affects the localization of and results in increased activity of [NFKB1 protein binds to RELA protein]]; Paclitaxel affects the localization of and results in increased activity of [NFKB1 protein binds to RELA protein]; Trimetazidine inhibits the reaction [Paclitaxel results in increased phosphorylation of RELA protein] | PMID:11123339 PMID:34654991 PMID:36898573 | | ||||||||||||||||||||||
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