GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bak1 | affects expression | ISO | BAK1 (Homo sapiens) | 6480464 | CTD | Paclitaxel affects the expression of BAK1 mRNA; Paclitaxel affects the expression of BAK1 protein | PMID:10822281 | Bak1 | increases expression | ISO | BAK1 (Homo sapiens) | 6480464 | CTD | Paclitaxel results in increased expression of BAK1 mRNA; Paclitaxel results in increased expression of BAK1 protein | PMID:10822281 PMID:24126434 | Bak1 | increases response to substance | ISO | BAK1 (Homo sapiens) | 6480464 | CTD | BAK1 protein results in increased susceptibility to Paclitaxel | PMID:17688235 | Bak1 | multiple interactions | ISO | Bak1 (Mus musculus) | 6480464 | CTD | [BAK1 protein mutant form co-treated with BAX protein mutant form] inhibits the reaction [Paclitaxel results in increased activity of and results in increased cleavage of CASP3 protein] | PMID:17652622 | |
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