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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307993
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcr
Name: BCR activator of RhoGEF and GTPase
Acc ID: CHEBI:45783
Term: imatinib
Definition: A benzamide obtained by formal condensation of the carboxy group of 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid with the primary aromatic amino group of 4-methyl-N(3)-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine. Used (as its mesylate salt) for treatment of chronic myelogenous leukemia and gastrointestinal stromal tumours.
Chemical ID: MESH:C097613
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
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