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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1562047 Species: Rattus norvegicus RGD Object: Gene Symbol: Cks2 Name: CDC28 protein kinase regulatory subunit 2

Acc ID: CHEBI:45713 Term: trans-resveratrol Definition: A resveratrol that has formula C14H12O3. CasRN: 501-36-0 Chemical ID: MESH:C059514

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:1348782	6480464	CTD	resveratrol results in decreased expression of CKS2 mRNA	PMID:15767336
multiple interactions	ISO	RGD:1348782	6480464	CTD	[Coumestrol co-treated with resveratrol] results in increased expression of CKS2 mRNA	PMID:19167446