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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69057 Species: Rattus norvegicus RGD Object: Gene Symbol: Nr1i2 Name: nuclear receptor subfamily 1, group I, member 2

Acc ID: CHEBI:45487 Term: 13-cis-retinal Definition: A retinal that has formula C20H28O. CasRN: 472-86-6 Chemical ID: MESH:C031338

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:69105	6480464	CTD	13-cis-retinal promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]	PMID:16632523