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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306847
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akr1c1
Name: aldo-keto reductase family 1, member C1
Acc ID: CHEBI:4513
Term: dicoumarol
Definition: A hydroxycoumarin that is methane in which two hydrogens have each been substituted by a 4-hydroxycoumarin-3-yl group. Related to warfarin, it has been used as an anticoagulant.
Chemical ID: MESH:D001728
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1c1decreases activityEXP 6480464CTDDicumarol results in decreased activity of AKR1C6 proteinPMID:16788056
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