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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61862
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gria2
Name: glutamate ionotropic receptor AMPA type subunit 2
Acc ID: CHEBI:44915
Term: propofol
Definition: A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Chemical ID: MESH:D015742
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gria2increases expressionEXP 6480464CTDPropofol results in increased expression of GRIA2 proteinPMID:28663055
Gria2multiple interactionsEXP 6480464CTDalpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid inhibits the reaction [Propofol results in increased expression of GRIA2 protein]PMID:28663055
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