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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621543
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Chek2
Name: checkpoint kinase 2
Acc ID: CHEBI:44442
Term: 6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine
Definition: null
Chemical ID: MESH:C475622
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chek2multiple interactionsISOCHEK2 (Homo sapiens)6480464CTD4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased phosphorylation of CHEK2 protein]PMID:26208482
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