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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313502 Species: Homo sapiens RGD Object: Gene Symbol: GPT2 Name: glutamic pyruvate transaminase (alanine aminotransferase) 2

Acc ID: CHEBI:44185 Term: methotrexate Definition: A pteridine that has formula C20H22N8O5. CasRN: 59-05-2 Chemical ID: MESH:D008727

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects expression	ISO	RGD:1313503	6480464	CTD	Methotrexate affects the expression of GPT2 mRNA	PMID:18502557