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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620795
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Src
Name: SRC proto-oncogene, non-receptor tyrosine kinase
Acc ID: CHEBI:43355
Term: indoxyl sulfate
Definition: An aryl sulfate that is indoxyl in which the hydroxyl hydrogen is substituted by a sulfo group.
Chemical ID: MESH:D007200
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srcincreases phosphorylationISOSrc (Mus musculus)6480464CTDIndican results in increased phosphorylation of SRC proteinPMID:23639249
Srcmultiple interactionsISOSrc (Mus musculus)6480464CTD[AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Indican results in increased phosphorylation of SRC protein]; [AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Indican results in increased phosphorylation of STAT3 protein]PMID:23639249
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