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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3344
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Plcb1
Name: phospholipase C beta 1
Acc ID: CHEBI:43000
Term: guanosine 5'-[gamma-thio]triphosphate
Definition: A nucleoside triphosphate analogue that has formula 539.24722.
Chemical ID: MESH:D016244
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plcb1increases activityEXP 6480464CTDGuanosine 5'-O-(3-Thiotriphosphate) results in increased activity of PLCB1 proteinPMID:15998294
Plcb1multiple interactionsEXP 6480464CTD[3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein; Caffeine inhibits the reaction [[3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein]; Caffeine inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased activity of PLCB1 protein]; Theophylline inhibits the reaction [[3,4-dihydroxyphenylglycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein]; Theophylline inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased activity of PLCB1 protein]PMID:15998294
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