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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619831 Species: Rattus norvegicus RGD Object: Gene Symbol: Fas Name: Fas (TNF receptor superfamily, member 6)

Acc ID: CHEBI:42977 Term: 25-hydroxycholesterol Definition: A 25-hydroxy steroid that has formula C27H46O2. CasRN: 2140-46-7 Chemical ID: MESH:C007997

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:1552455	6480464	CTD	25-hydroxycholesterol results in increased expression of FAS mRNA	PMID:19260826