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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69313 Species: Rattus norvegicus RGD Object: Gene Symbol: Ache Name: acetylcholinesterase

Acc ID: CHEBI:42944 Term: galanthamine Definition: A benzazepine alkaloid that has formula C17H21NO3. CasRN: 357-70-0 Chemical ID: MESH:D005702

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases activity	ISO	RGD:735878	6480464	CTD	Galantamine results in decreased activity of ACHE protein	PMID:14535624
decreases activity	EXP		6480464	CTD	Galantamine results in decreased activity of ACHE protein	PMID:19345205
decreases activity	EXP		6480464	CTD	Galantamine results in decreased activity of ACHE protein	PMID:18571635 PMID:19345205
decreases activity	ISO	RGD:735878	6480464	CTD	Galantamine results in decreased activity of ACHE protein	PMID:14535624 PMID:18573242