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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61867
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp9
Name: caspase 9
Acc ID: CHEBI:4286
Term: 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid
Definition: A 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid that has formula C16H10N2O6S4.
Chemical ID: MESH:D017878
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp9multiple interactionsISOCASP9 (Homo sapiens)6480464CTD4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein]; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone results in increased cleavage of CASP9 protein]PMID:14766669 PMID:28343033
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