GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp9 | decreases expression | EXP | | 6480464 | CTD | Glucose results in decreased expression of MMP9 protein | PMID:31838053 | Mmp9 | multiple interactions | EXP | | 6480464 | CTD | [Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of MMP9 protein]; farrerol inhibits the reaction [Glucose results in decreased expression of MMP9 mRNA]; farrerol inhibits the reaction [Glucose results in decreased expression of MMP9 protein]; Glucose affects the reaction [Azoxymethane affects the expression of MMP9 protein] | PMID:22467055 PMID:31838053 | Mmp9 | decreases activity | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | Glucose deficiency results in decreased activity of MMP9 protein | PMID:35427737 | Mmp9 | increases expression | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | Glucose results in increased expression of MMP9 mRNA | PMID:28478229 PMID:31655124 | Mmp9 | multiple interactions | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | [Glucose co-treated with Resveratrol] results in decreased expression of MMP9 mRNA; Glucose promotes the reaction [Air Pollutants results in increased activity of MMP9 protein]; Glucose promotes the reaction [Air Pollutants results in increased expression of MMP9 mRNA]; Glucose promotes the reaction [JUN protein binds to MMP9 promoter]; Glucose promotes the reaction [PARP1 protein binds to MMP9 promoter]; Glucose promotes the reaction [Particulate Matter results in increased activity of MMP9 protein]; Glucose promotes the reaction [Particulate Matter results in increased expression of MMP9 mRNA]; Glucose promotes the reaction [RELA protein binds to MMP9 promoter]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose promotes the reaction [JUN protein binds to MMP9 promoter]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose promotes the reaction [RELA protein binds to MMP9 promoter]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose results in increased expression of MMP9 mRNA]; PARP1 protein affects the reaction [Glucose promotes the reaction [JUN protein binds to MMP9 promoter]]; PARP1 protein affects the reaction [Glucose promotes the reaction [RELA protein binds to MMP9 promoter]]; PARP1 protein affects the reaction [Glucose results in increased expression of MMP9 mRNA]; SB 203580 inhibits the reaction [Glucose promotes the reaction [Air Pollutants results in increased activity of MMP9 protein]]; SB 203580 inhibits the reaction [Glucose promotes the reaction [Particulate Matter results in increased activity of MMP9 protein]]; SIRT1 protein inhibits the reaction [Glucose promotes the reaction [PARP1 protein binds to MMP9 promoter]] | PMID:24064760 PMID:26179980 PMID:28478229 | Mmp9 | multiple interactions | ISO | Mmp9 (Mus musculus) | 6480464 | CTD | [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of MMP9 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of MMP9 protein; [Resveratrol co-treated with Glucose] results in decreased activity of MMP9 protein; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of MMP9 mRNA]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of MMP9 protein]; U 0126 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of MMP9 mRNA]; U 0126 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of MMP9 protein] | PMID:24659233 PMID:24682241 | | ||||||||||||||||||||||
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