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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2092
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akr1b1
Name: aldo-keto reductase family 1 member B1
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1b1increases expressionISOAkr1b1 (Mus musculus)6480464CTDGlucose results in increased expression of AKR1B1 mRNA; Glucose results in increased expression of AKR1B1 proteinPMID:16805838
Akr1b1multiple interactionsISOAKR1B1 (Homo sapiens)6480464CTDAKR1B1 protein promotes the reaction [Glucose results in increased abundance of Sorbitol]PMID:25451566
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