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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620404 Species: Rattus norvegicus RGD Object: Gene Symbol: Adam17 Name: ADAM metallopeptidase domain 17

Acc ID: CHEBI:42638 Term: flufenamic acid Definition: An aromatic amino acid consisting of anthranilic acid carrying an N-(trifluoromethyl)phenyl substituent. CasRN: 530-78-9 Chemical ID: MESH:D005439

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases response to substance	ISO	RGD:731401	6480464	CTD	ADAM17 results in increased susceptibility to Flufenamic Acid	PMID:12147693