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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69328 Species: Rattus norvegicus RGD Object: Gene Symbol: Cdkn1a Name: cyclin-dependent kinase inhibitor 1A

Acc ID: CHEBI:42567 Term: fisetin Definition: A 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3' and 4'. CasRN: 528-48-3 Chemical ID: MESH:C017875

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:735341	6480464	CTD	[Cisplatin co-treated with fisetin] results in increased expression of CDKN1A protein	PMID:21216935
increases expression	ISO	RGD:735341	6480464	CTD	fisetin results in increased expression of CDKN1A protein	PMID:21216935