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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3112
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc1
Name: ATP binding cassette subfamily C member 1
Acc ID: CHEBI:42491
Term: flavone
Definition: The simplest member of the class of flavones that consists of 4H-chromen-4-one bearing a phenyl substituent at position 2.
Chemical ID: MESH:C043562
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc1decreases activityISOABCC1 (Homo sapiens)6480464CTDflavone results in decreased activity of ABCC1 proteinPMID:15041478
Abcc1multiple interactionsISOABCC1 (Homo sapiens)6480464CTDflavone inhibits the reaction [ABCC1 protein affects the export of S-(2,4-dinitrophenyl)glutathione]PMID:15041478
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