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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10551
Species: Mus musculus
RGD Object: Gene
Symbol: Esr1
Name: estrogen receptor 1 (alpha)
Acc ID: CHEBI:42068
Term: idarubicin
Definition: An anthracycline antibiotic that has formula 497.49392.
Chemical ID: MESH:D015255
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Esr1decreases activityISOESR1 (Homo sapiens)6480464CTDIdarubicin results in decreased activity of ESR1 proteinPMID:25257666
Esr1increases activityISOESR1 (Homo sapiens)6480464CTDIdarubicin results in increased activity of ESR1 proteinPMID:25257666
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