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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631345 Species: Rattus norvegicus RGD Object: Gene Symbol: Abcg2 Name: ATP-binding cassette, subfamily G (WHITE), member 2

Acc ID: CHEBI:41977 Term: daunorubicin Definition: A natural product found in Actinomadura roseola. CasRN: 20830-81-3 Chemical ID: MESH:D003630

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:1352615	6480464	CTD	Dactinomycin inhibits the reaction [Daunorubicin results in increased expression of ABCG2 mRNA]	PMID:20019844
increases expression	ISO	RGD:1352615	6480464	CTD	Daunorubicin results in increased expression of ABCG2 mRNA	PMID:20019844