GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Akt1 | decreases phosphorylation | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | Daunorubicin results in decreased phosphorylation of AKT1 protein | PMID:34963561 | Akt1 | decreases response to substance | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | AKT1 protein results in decreased susceptibility to Daunorubicin | PMID:22252735 | Akt1 | multiple interactions | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole co-treated with AKT1 protein] inhibits the reaction [Daunorubicin results in decreased expression of MCL1 mRNA]; [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole co-treated with AKT1 protein] inhibits the reaction [Daunorubicin results in decreased expression of MCL1 protein]; Acetylcysteine inhibits the reaction [Daunorubicin results in decreased phosphorylation of AKT1 protein]; AKT1 protein inhibits the reaction [Daunorubicin results in decreased expression of MCL1 mRNA]; AKT1 protein inhibits the reaction [Daunorubicin results in decreased expression of MCL1 protein]; AKT1 protein inhibits the reaction [Daunorubicin results in decreased expression of SP1 protein]; AKT1 protein inhibits the reaction [Daunorubicin results in decreased phosphorylation of MAPK1 protein]; AKT1 protein inhibits the reaction [Daunorubicin results in decreased phosphorylation of MAPK3 protein] | PMID:34963561 | | ||||||||||||||||||||||
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