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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2326
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cebpa
Name: CCAAT/enhancer binding protein alpha
Acc ID: CHEBI:41922
Term: diethylstilbestrol
Definition: An olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups.
Chemical ID: MESH:D004054
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cebpaincreases expressionEXP 6480464CTDDiethylstilbestrol results in increased expression of CEBPA mRNAPMID:37077353
Cebpaincreases expressionISOCebpa (Mus musculus)6480464CTDDiethylstilbestrol results in increased expression of CEBPA mRNA; Diethylstilbestrol results in increased expression of CEBPA proteinPMID:22710028
Cebpamultiple interactionsISOCebpa (Mus musculus)6480464CTD2-chloro-5-nitrobenzanilide inhibits the reaction [Diethylstilbestrol results in increased expression of CEBPA protein]PMID:22710028
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