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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734348 Species: Homo sapiens RGD Object: Gene Symbol: PIP4K2A Name: phosphatidylinositol-5-phosphate 4-kinase, type II, alpha

Acc ID: CHEBI:41879 Term: dexamethasone Definition: A fluorinated steroid that has formula C22H29FO5. CasRN: 50-02-2 Chemical ID: MESH:D003907

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:621708	6480464	CTD	Dexamethasone results in decreased expression of PIP4K2A mRNA	PMID:20032058
multiple interactions	ISO	RGD:621708	6480464	CTD	Testosterone inhibits the reaction [Dexamethasone results in decreased expression of PIP4K2A mRNA]	PMID:20032058