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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62219 Species: Mus musculus RGD Object: Gene Symbol: Gjb1 Name: gap junction protein, beta 1

Acc ID: CHEBI:41879 Term: dexamethasone Definition: A fluorinated steroid that has formula C22H29FO5. CasRN: 50-02-2 Chemical ID: MESH:D003907

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:61926	6480464	CTD	Dexamethasone results in decreased expression of GJB1 mRNA	PMID:17522070
increases expression	EXP		6480464	CTD	Dexamethasone results in increased expression of GJB1 mRNA	PMID:21621594