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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11414 Species: Mus musculus RGD Object: Gene Symbol: Th Name: tyrosine hydroxylase

Acc ID: CHEBI:41879 Term: dexamethasone Definition: A fluorinated steroid that has formula C22H29FO5. CasRN: 50-02-2 Chemical ID: MESH:D003907

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:3853	6480464	CTD	Dexamethasone results in increased expression of TH protein	PMID:14550852
decreases expression	ISO	RGD:3853	6480464	CTD	Dexamethasone results in decreased expression of TH mRNA	PMID:11072875