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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731981
Species: Homo sapiens
RGD Object: Gene
Symbol: KCNMA1
Name: potassium calcium-activated channel subfamily M alpha 1
Acc ID: CHEBI:41774
Term: tamoxifen
Definition: A stilbenoid that has formula 371.51460.
Chemical ID: MESH:D013629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KCNMA1multiple interactionsEXP 6480464CTDTamoxifen inhibits the reaction [Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]]; Tamoxifen inhibits the reaction [Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]]PMID:21413024
KCNMA1multiple interactionsISOKcnma1 (Rattus norvegicus)6480464CTD[bexarotene co-treated with Tamoxifen] results in decreased expression of KCNMA1 mRNAPMID:17630414
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