GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp9 | increases activity | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | Tamoxifen analog results in increased activity of CASP9 protein; Tamoxifen results in increased activity of CASP9 protein | PMID:14990993 PMID:32530119 | Casp9 | increases cleavage | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | Tamoxifen results in increased cleavage of CASP9 protein | PMID:17767197 | Casp9 | multiple interactions | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | [[methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein; [methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP9 protein; [Tamoxifen co-treated with Quercetin] affects the activity of CASP9 protein; [Tamoxifen co-treated with TNFSF10 protein] results in increased cleavage of CASP9 protein; AKT1 protein inhibits the reaction [Tamoxifen analog results in increased activity of CASP9 protein]; AKT1 protein inhibits the reaction [Tamoxifen results in increased activity of CASP9 protein] | PMID:14990993 PMID:17767197 PMID:18790785 PMID:32530119 | | ||||||||||||||||||||||
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